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1

Advances in understanding and treatment of Tourette syndrome

McNaught, Kevin St. P., Mink, Jonathan W.

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Year:

2011

Language:

english

File:

PDF, 574 KB

english, 2011

2

Lewy-body formation is an aggresome-related process: a hypothesis

C Warren Olanow, Daniel P Perl, George N DeMartino, Kevin St P McNaught

Journal:

The Lancet Neurology

Year:

2004

Language:

english

File:

PDF, 3.46 MB

english, 2004

3

Proteolytic stress: A unifying concept for the etiopathogenesis of Parkinson's disease

Kevin St. P. McNaught, C. Warren Olanow

Journal:

Annals of Neurology

Year:

2003

Language:

english

File:

PDF, 766 KB

english, 2003

4

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

Kevin St. P. McNaught, Daniel P. Perl, Anna-Liisa Brownell, C. Warren Olanow

Journal:

Annals of Neurology

Year:

2004

Language:

english

File:

PDF, 1.49 MB

english, 2004

5

Brainstem pathology in DYT1 primary torsion dystonia

Kevin St. P. McNaught, Alexander Kapustin, Tehone Jackson, Toni-Ann Jengelley, Ruth JnoBaptiste, Pullanipally Shashidharan, Daniel P. Perl, Pedro Pasik, C. Warren Olanow

Journal:

Annals of Neurology

Year:

2004

Language:

english

File:

PDF, 1.68 MB

english, 2004

6

Proteasome inhibitor–induced model of Parkinson's disease

Kevin St. P. McNaught, C. Warren Olanow

Journal:

Annals of Neurology

Year:

2006

Language:

english

File:

PDF, 722 KB

english, 2006

7

Ubiquitin–proteasome system and Parkinson's disease

C. Warren Olanow, Kevin St. P. McNaught

Journal:

Movement Disorders

Year:

2006

Language:

english

File:

PDF, 546 KB

english, 2006

8

Aggresome-related biogenesis of Lewy bodies

Kevin St P. McNaught, P. Shashidharan, Daniel P. Perl, Peter Jenner, C. Warren Olanow

Journal:

European Journal of Neuroscience

Year:

2002

Language:

english

File:

PDF, 732 KB

english, 2002

9

Nitric Oxide Causes Glutamate Release from Brain Synaptosomes

Kevin St. P. McNaught, Guy C. Brown

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 621 KB

english, 1998

10

Altered Glial Function Causes Neuronal Death and Increases Neuronal Susceptibility to 1-Methyl-4-Phenylpyridinium- and 6-Hydroxydopamine-Induced Toxicity in Astrocytic/Ventral Mesencephalic Co-Cultures

Kevin St. P. MCNaught, Peter Jenner

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 161 KB

english, 1999

11

Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

Kevin St P. McNaught, Catherine Mytilineou, Ruth JnoBaptiste, Jocelyn Yabut, P. Shashidharan, Peter Jenner, C. Warren Olanow

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 172 KB

english, 2002

12

Overexpression of torsinA in PC12 cells protects against toxicity

P. Shashidharan, Nicolae Paris, Daniela Sandu, Laina Karthikeyan, Kevin St P. McNaught, Ruth H. Walker, C. Warren Olanow

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 251 KB

english, 2004

13

The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease

Kevin St.P. Mcnaught, Ruth Jnobaptiste, Tehone Jackson, Toni-Ann Jengelley

Journal:

Year:

2010

Language:

english

File:

PDF, 767 KB

english, 2010

14

Parkin-mediated regulation of mitochondrial dynamics

Kevin St. P. McNaught

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 83 KB

english, 2011

15

OPINION: Failure of the ubiquitin–proteasome system in Parkinson's disease

McNaught, Kevin St P., Olanow, C. Warren, Halliwell, Barry, Isacson, Ole, Jenner, Peter

Journal:

Nature Reviews Neuroscience

Year:

2001

Language:

english

File:

PDF, 254 KB

english, 2001

16

Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation

Kevin St.P McNaught, Peter Jenner

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 358 KB

english, 2000

17

Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson’s disease

Kevin St.P. McNaught, Pierre-Alain Carrupt, Cosimo Altomare, Saverio Cellamare, Angelo Carotti, Bernard Testa, Peter Jenner, C.David Marsden

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 469 KB

english, 1998

18

Altered Proteasomal Function in Sporadic Parkinson's Disease

Kevin St. P. McNaught, Roger Belizaire, Ole Isacson, Peter Jenner, C.Warren Olanow

Journal:

Experimental Neurology

Year:

2003

Language:

english

File:

PDF, 371 KB

english, 2003

19

Inhibition of monoamine oxidase by isoquinoline derivatives: Qualitative and 3D-quantitative structure-activity relationships

Ulrike Thull, Silvia Kneubühler, Patrick Gaillard, Pierre-Alain Carrupt, Bernard Testa, Cosimo Altomare, Angelo Carotti, Peter Jenner, Kevin St. P. McNaught

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 791 KB

english, 1995

20

Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)

Kevin ST.P. McNaught, Ulrike Thull, Pierre-Alain Carrupt, Cosimo Altomare, Saverio Cellamare, Angelo Carotti, Bernard Testa, Peter Jenner, C.David Marsden

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 1.08 MB

english, 1995

21

Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration

Kevin St.P. McNaught, Ulrike Thull, Pierre-Alain Carrupt, Cosimo Altomare, Saverio Cellamare, Angelo Carotti, Bernard Testa, Peter Jenner, C.David Marsden

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.05 MB

english, 1996

22

Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Kevin St.P. McNaught, Ulrike Thull, Pierre-Alain Carrupt, Cosimo Altomare, Saverio Cellamare, Angelo Carotti, Bernard Testa, Peter Jenner, C.David Marsden

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 778 KB

english, 1996

23

Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Kevin St.P. McNaught, Ulrike Thull, Pierre-Alain Carrupt, Cosimo Altomare, Saverio Cellamare, Angelo Carotti, Bernard Testa, Peter Jenner, C. David Marsden

Journal:

Neuroscience Letters

Year:

1996

Language:

english

File:

PDF, 387 KB

english, 1996

24

Generation and characterization of Dyt1 ΔGAG knock-in mouse as a model for early-onset dystonia

Mai T. Dang, Fumiaki Yokoi, Kevin St. P. McNaught, Toni-Ann Jengelley, Tehone Jackson, Jianyong Li, Yuqing Li

Journal:

Experimental Neurology

Year:

2005

Language:

english

File:

PDF, 532 KB

english, 2005

25

Protein aggregation in the pathogenesis of familial and sporadic Parkinson's disease

Kevin St. P. McNaught, C. Warren Olanow

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 395 KB

english, 2006

26

Dysfunction of rat forebrain astrocytes in culture alters cytokine and neurotrophic factor release

Kevin St.P McNaught, Peter Jenner

Journal:

Neuroscience Letters

Year:

2000

Language:

english

File:

PDF, 172 KB

english, 2000

27

Proteasomal function is impaired in substantia nigra in Parkinson's disease

Kevin St.P McNaught, Peter Jenner

Journal:

Neuroscience Letters

Year:

2001

Language:

english

File:

PDF, 97 KB

english, 2001

28

Selective loss of 20S proteasome α-subunits in the substantia nigra pars compacta in Parkinson's disease

Kevin St.P McNaught, Roger Belizaire, Peter Jenner, C.Warren Olanow, Ole Isacson

Journal:

Neuroscience Letters

Year:

2002

Language:

english

File:

PDF, 336 KB

english, 2002

29

Nigral Cell Loss Produced by Infusion of Isoquinoline Derivatives Structurally Related to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine

Kevin St.P. McNaught, Ulrike Thull, Pierre-Alain Carrupt, Cosimo Altomare, Saverio Cellamare, Angelo Carotti, Bernard Testa, Peter Jenner, C.David Marsden

Journal:

Neurodegeneration

Year:

1996

Language:

english

File:

PDF, 397 KB

english, 1996

30

Progress in research on Tourette syndrome

Black, Kevin J., Jankovic, Joseph, Hershey, Tamara, McNaught, Kevin St. P., Mink, Jonathan W., Walkup, John

Journal:

Journal of Obsessive-Compulsive and Related Disorders

Year:

2014

Language:

english

File:

PDF, 353 KB

english, 2014

31

[Handbook of Clinical Neurology] Parkinson's Disease and Related Disorders, Part I Volume 83 || Protein‐handling dysfunction in Parkinson's disease

McNaught, Kevin St. P.

Year:

2007

Language:

english

File:

PDF, 886 KB

english, 2007

32

[International Review of Neurobiology] Volume 62 || Proteolytic Dysfunction in Neurodegenerative Disorders

McNaught, Kevin St.P.

Year:

2004

Language:

english

File:

PDF, 287 KB

english, 2004

33

Proteasome inhibition causes nigral degeneration with inclusion bodies in rats

McNaught, Kevin St. P., Bj??rklund, Lars M., Belizaire, Roger, Isacson, Ole, Jenner, Peter, Olanow, C. Warren

Journal:

Year:

2002

Language:

english

File:

PDF, 312 KB

english, 2002

34

Inhibition of ??-Ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

McNaught, Kevin St.P., Altomare, Cosimo, Cellamare, Saverio, Carotti, Angelo, Thull, Ulrike, Carrupt, Pierre-Alain, Testa, Bernard, Jenner, Peter, Marsden, C. David

Journal:

Year:

1995

File:

PDF, 327 KB

1995

35

Inhibition of α-Ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

McNaught, Kevin St. P., Altomare, Cosimo, Cellamare, Saverio, Carotti, Angelo, Thull, Ulrike, Carrupt, Pierre-Alain, Testa, Bernard, Jenner, Peter, Marsden, C. David

Journal:

Year:

1995

File:

PDF, 327 KB

1995

36

Nitric oxide causes release of glutamate from brain synaptosomes

MCNAUGHT, KEVIN St.P., BROWN, GUY C.

Journal:

Biochemical Society Transactions

Year:

1997

Language:

english

File:

PDF, 145 KB

english, 1997

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